US Okays Emergency Drug for Covid-19

The U.S. Food and Drug Administration has granted an emergency use authorization to remdesivir, an antiviral drug, to treat Covid-19. (Photo: Gilead Sciences Inc/Handout via REUTERS)


Recent studies showed mixed results about remdesivir’s effectiveness in treating the new coronavirus.

The US Food and Drug Administration on Friday authorized remdesivir, an experimental antiviral drug, for emergency use to treat Covid-19.

The authorization allows the intravenous drug to be distributed to doctors to administer to patients with severe disease, namely patients with low blood oxygen or those needing breathing assistance with a mechanical ventilator.

Many health experts have had high hopes for the drug, which was initially developed by Gilead Sciences to treat Ebola, and it has since been used in experiments to treat the coronaviruses SARS and MERS. That early testing gave remdesivir a head start in the race for a treatment to Covid-19.

But despite the release of some early study results this week, it’s still not clear how effective the drug is at fighting the virus, and more research is needed before it can be used as the default treatment.

Remdesivir previously showed some success in animal models. Now, early results from a clinical trial at the National Institutes of Health (NIH) show that Covid-19 patients who took remdesivir recovered 31 percent faster than those prescribed a placebo. An internal study from Gilead also found that the drug was just as effective over five days of use as it is over 10.

Dr. Anthony Fauci, director of the National Institute of Allergy and Infectious Diseases, told reporters at the White House on April 29 that he thought the findings were significant.

“This is really quite important,” he said. “This will be the standard of care.”

But a randomized trial of the drug in China recently published in the Lancet found that there was no statistical benefit to taking the drug.

Taken together, the studies highlight the need for more studies. Remdesivir may or may not work, but it’s hard to say based on the evidence available at this point.

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