Archive for the 'Health' Category

Yared Tekabe Uses Molecular Imaging for Early Detection of Heart Disease

Dr. Yared Tekabe runs studies in cardiovascular disease detection and prevention at Columbia University. (Photo: Tekabe at his office at William Black building in upper Manhattan - Courtesy photograph)

Tadias Magazine
By Tseday Alehegn

Published: Wednesday, January 25, 2012

New York (TADIAS) – In Spring 2009, we featured Dr. Yared Tekabe’s groundbreaking work on non-invasive atherosclerosis detection and molecular imaging, which was published in the American Heart Association´s journal, Circulation. As in most chronic heart disease conditions, the plaque that accumulates in blood vessels is usually not detected until it leads to serious, and often fatal, blockages of blood supply such as during an episode of heart attack or stroke. Having received a $1.6 million grant from the National Institute of Health Tekabe’s research focused on the use of novel molecular imaging techniques to identify sites of inflammation that can help us with early detection of atherosclerosis.

In 2010, his work was highlighted in Osborn & Jaffer’s review entitled “The Year in Molecular Imaging,” noting that Tekabe and colleagues had developed a tracer that imaged RAGE — a receptor for advanced glycation end products, which is implicated in a host of inflammation-related diseases including artherosclerosis, cancer, diabetes and alzheimer’s. Tekabe’s group, along with his colleague Dr. Ann Marie Schmidt, holds a patent for this RAGE-directed imaging technology.

Tekabe’s lab also used similar imaging technology to detect RAGE in mouse models who had artifically-induced ischemia (restriction of blood supply) in their left anterior descending coronary artery, which is the main supplier of blood to the left ventricle. When blood supply is restored (reperfusion), the sudden change may also cause further inflammation and tissue damage from impact. By being able to trace RAGE and pathways of inflammation using molecular imaging techniques, Tekabe has demonstrated that the highest RAGE expressing cells were the injured heart muscle cells undergoing programmed cell death.

Tekabe’s research in myocardial ischemic/reperfusion injury showed that RAGE could be traced in areas of inflammation in a non-invasive manner in live mouse subjects. The findings were presented at the 2011 World Molecular Imaging Congress scientific session, and was published in the Journal of the American College of Cardiology in January 2012. An editorial entitled ‘Visualizing the RAGE: Molecular Imaging After MI Provides Insight Into a Complex Receptor” accompanied Tekabe’s article, and emphasized that Tekabe’s research “continues to provide a solid foundation and proof of concept” that non-invasive imaging of RAGE following induced myocardial ischemia “is feasible” in live subjects.

Tekabe’s findings also have important implications for future antibody therapy formulations that can be used to treat RAGE-related chronic conditions. Tekabe hopes to translate his studies on mouse models to larger mammals and eventually to humans. Molecular imaging studies such as the one Tekabe has undertaken are critical in prevention of chronic cardiac conditions and could potentially decrease the number of sudden deaths from heart attack as it may allow physicians to make early and life-saving diagnoses.

When asked if there was anything else that he’d like to share with our readers, Dr. Tekabe replied, “Oh yes, since childhood, apart from my research, I’ve always wanted to involve myself in an Ethiopian movie, acting as the main character. Like in a love story. I hope to do this someday.”

Tseday Alehegn is Co-Founder & Editor-in-Chief of Tadias Magazine.

Related:
Yared Tekabe’s Groundbreaking Research in Heart Disease (TADIAS – March 17th, 2009)

Shiro, The Sure Thing: Why It’s Good For You

As we welcome the holiday season and the tradition of sharing food and thanks with loved ones, we thought it worthwhile to take a moment to reflect on Ethiopia’s rich food traditions. In this piece Dr. Asqual Getaneh invites us to look at one dish in particular – the shiro.

Tadias Magazine
By Dr. Asqual Getaneh

Saturday, November 26, 2011

New York (TADIAS) – Whether or not it is made from toasted or raw beans, cooked thick or thin, spiced up or buttered, shiro along with other legumes is perhaps the most nourishing, ubiquitous and affordable dish in Ethiopia. Unfortunately, shiro appears less frequently on dinner tables as a result of economic and social success. The trend is an irrational and en masse adoption of Western commercial diets (along with culture and politics); yet, the same diets are the main culprits for the growing health problem in the U.S. and Europe. We grab on fistfuls of processed foods in beautifully designed packets in lieu of our traditional diet. In this, we, Ethiopians, are not alone. Very few traditions have successfully resisted the marketing lure and the temptation of colorfully wrapped easy-to-cook and ready-to-eat meals. It does not help, that no one celebrates with shiro and that it is used to express pity or religious compunction. As a result, shiro recedes even further from our esteem and creative culinary imaginations.

Against this tide, we would like to argue that shiro and other legumes should be celebrated victuals in Ethiopian households (and non-Ethiopian households) for the following reasons. First, shiro is a healthy source of both macro-and micro-nutrients. Depending on regional preferences, a typical shiro dish is made from one of three legumes, broad (fava) beans, chick peas (garbanzo) or round peas, or as in the current trend, from flour mixture of all three beans. Although there are some differences in nutrient content, each of these legumes is a low fat source of protein, carbohydrate, fiber, iron and folate, among numerous other vitamins and minerals.

For those of you worried about getting adequate protein from beans, according to the USDA the average woman and man require 46 grams and 51 grams of protein per day respectively. However, for elite athletes the daily requirement is as high as 1.37 grams per kilograms of body weight per day. A cup of shiro provides about 16.3 grams of protein. Compare this with 20 grams of protein in a serving of chicken breast, 19 grams in salmon and 22 grams in beef steak.

Second, shiro is usually served with tomato salad and vegetables such as collard greens (gomen), cabbage, or string beans and carrot (fasolia), dishes that are rich in vitamin A and C. In addition gomen and cabbage have vitamin K and folate and are filled with phytochemicals including diindolymethane, and sulforaphane — antioxidants that boost the body’s cancer fighting potential. Carrots and tomatoes have carotenoids and tomatoes contain lycopene — a specific type of carotenoid that has a strong antioxidant property. When mixed with berbere, shiro provides additional vitamin A.

Shiro as many other Ethiopian dishes is never eaten without injera, preferably injera made of teff -a super grain that rivals quinoa in its proportional protein and superior calcium and iron content. In sufficient quantities, Teff also provides a third of the daily requirement for riboflavin, niacin, vitamin B6, folate and other micronutrients. Those of us living in the United States and outside of the Washington DC area, are not lucky enough to easily obtain teff-based injera and have to resort to various other combinations that are not as nutritious and that can be more calorie dense than teff-based injera. So, when consuming non-teff based injera, it is prudent to assess calorie and carbohydrate content, especially if one is concerned about obesity, metabolic diseases or have diabetes.

Third, “shiro yum!”. Ok, we may be shooting for the stars trying to sell creamy delicious shiro to kurt-loving readers and during the holiday season. But get into your meditative zone and consider all the possible flavors in shiro like coriander, cardamom, garlic, and berbere; also visualize other bean dishes like buticha, yeshimbra asa and ful. And, if only for an interesting addition to your bean dish cornucopia, foray into the unique land of hilbet, boquilt, siljo, or gulban. I guarantee if not your taste buds your body will be tingling happily. To err is human, so if you are not convinced enough to have shiro and other legumes frequently, we hope that this will at least engage your culinary imagination to include shiro in some form in your diet.

In sum, shiro is a great source of protein; and when combined with vegetables and tomato salad shiro-based meals provide almost all of the average daily requirements of folate, vitamin A, C and K. Include the goodness of teff and the meal will have additional micronutrients such as iron, calcium and vitamin B6. For individuals concerned about carbohydrates, injera made of teff has low glycemia load by virtue of its proportional fiber and protein content (estimated glycemia load of 84 for a cup of uncooked teff, compare this to 104 for a cup of uncooked rice). Add the antioxidant properties of carotenoids and phytochemicals, and shiro and its accompaniments are now in the realm of food-as-medicine. Above all shiro tastes heavenly. At a minimum, we should curb our flight into the dizzying glitter of substitute foods, even as many in the West reverse their course through the growing slow, organic, farm-to-table and locovore food movements.

Dr. Asqual Getaneh is an Associate Clinical Professor of Medicine at Columbia University in New York and a contributor to Tadias Magazine.

Related:
Our Beef with Kitfo: Are Ethiopians in America Subscribing to the Super Sizing of Food?

Cover image: operagirlcooks.com.

GHCG Announces 4th Medical Mission to Ethiopia

Above: The Ethio-American NGO Gemini Health Care Group
says it’s ready for its upcoming medical mission to Ethiopia.

Tadias Magazine
Health News Update

Published: Tuesday, March 15, 2011

New York (Tadias) – Gemini Health Care Group (GHCG), a U.S.-based Ethiopian American NGO that focuses on pediatric training and assistance to medical professionals in Ethiopia, launched its 4th annual educational and medical mission in March 2011.

“Beginning on March 18th, the GHCC Board members as well as eighteen health care professionals will be in Addis Ababa, Ethiopia to provide teaching and service,” says Dr. Ebba K. Ebba, the group’s Founder and President. “The pediatric sub-specialists in the areas of pediatric ENT, Ophthalmology, Audiology, Anesthesia, and Urology will be providing training and medical assistance at Black Lion Hospital, Cure Hospital and Mekanissa School for the Deaf. This portion of the medical mission is being organized in collaboration with Healing the Children, Greater Philadelphia Chapter.”

During the team’s last trip to Addis they treated young people including 8-year-old Zemen Toshome, whose story was highlighted by Opinion Columnist Harold Jackson in the Philadelphia Inquirer. Jackson wrote: “For more than six years, Zemen has lived at Tikur Anbesa (Black Lion) Hospital in Addis Ababa. He goes outside only briefly on the hospital grounds. He can’t shout because of his medical condition. Zemen has laryngeal papillomatosis, a disease in which tumors grow inside the larynx, vocal cords, or respiratory tract. The disease occurs when the human papillomavirus (HPV) is transferred from a mother to her child at birth. The tumors can grow quickly and cause difficulty in breathing, which if not corrected can lead to death.”

“The second part of our medical mission includes a one‐week educational mission to pediatric residents and medical students at the Black Lion Hospital as well as to other community pediatricians,” Dr. Ebba says. “We have recruited four pediatric specialists in the areas of pediatric Pulmonology, Endocrinology, Neurology and Emergency medicine to be participants at the First Annual Pediatrics by the Nile.”

The latter is a medical education conference to be held in Addis Ababa, Ethiopia. The conference, which is being co‐sponsored by the Ethiopian Pediatric Society, is scheduled to take place on Thursday March 31, 2011 and Friday, April 1, 2011 at the Addis Ababa Hilton.

You can learn more about Gemini Health Care Group at: www.GHCG.org.

Cover photo courtesy of GHCG.

Video: Dr. Ebba K. Ebba, Founder of Gemini Health Care Group, on 50 in 52 interview (2009)

Reducing Childbirth Injuries In Ethiopia

Above: ‘Today Show’ correspondent Jenna Bush Hager travels to
Ethiopia to shine light on maternal health. (Photo: Screen shot)

Tadias Magazine
By Tadias Staff

Published: Wednesday, December 29, 2010

New York (Tadias) – “It is the oldest medical cause in the world. There is currency dug out of pyramids containing images of fistula, yet in the 21st century it is the most neglected cause,” Dr. Catherine Hamlin, Founder of the Addis Ababa Fistula Hospital, said in an interview with Tadias Magazine a few years ago. She was speaking about a childbirth injury that affects one out of every 12 women in Africa and approximately three million women worldwide. In developing nations, such as Ethiopia, where access to hospitals in remote areas are difficult to find, young women suffer from obstructive labor and other childbirth related health issues, which can otherwise be successfully alleviated with adequate medical support. Unassisted labor in such conditions may lead to bladder, vaginal, and rectum injuries that incapacitate and stigmatize these women.

In the following MSNBC ‘Today Show’ video, contributing correspondent Jenna Bush Hager (the daughter of former President George W. Bush), travels to Ethiopia to shine light on maternal health. She focuses on the efforts underway by the non-profit organization CARE, in collaboration with local authorities, helping women to survive childbirth injuries. The segment makes the case for continued humanitarian U.S. assistance to reduce one of the world’s highest rates of maternal and infant mortalities. According to USAID, more than 500,000 women and girls in Ethiopia suffer from disabilities resulting from complications during pregnancy and childbirth each year, and over 25,000 women and girls die annually due to pregnancy–related complications.

Watch:

Visit msnbc.com for breaking news, world news, and news about the economy

Farmers in Kansas seek to expand test plots of Ethiopian grain into marketable fields of teff

Above: Teff is gluten free and known for its flood and drought
resistance. This year 150 acres was planted in Kansas, down
from the 250 acres projected due to untimely rains. (Injera)

By Roxana Hegeman

WICHITA, Kan. (AP) – When black farmers in Kansas first began growing an Ethiopian cereal grain known as teff five years ago, they were intrigued by the crop’s connection to Africa.

Now, the Kansas Black Farmers Association is working with conservationists to expand test plots of teff into market-sized fields that farmers across the state can plant as an alternative crop.

“We get calls monthly from people wanting any teff we have so they can mill it for food,” said Darla Juhl, coordinator for the conservationists group, Solomon Valley Resource Conservation and Development Area. Some of those calls have come from people as far away as the Netherlands and Mexico.

Teff is gluten free and known for its flood and drought resistance. Read more.

Related from Tadias Archives:
Teff luck: What Has Piracy Got To Do With The Price of Injera?

Above: The media never resists stories of sea attacks, but
there is another type of piracy that hardly gets attention:
the looming intellectual property warfare in Africa.

Tadias Magazine
By Nemo Semret

Published: Sunday, January 31, 2010

New York (Tadias) – A few months ago, three Somalis pirates were at the center of world news as they haplessly tried to extort money from an American ship in the Indian Ocean. Three guys coming out of an anarchic isolated part of the world, risked their lives at sea. Two were killed and one now faces the death penalty in the US. Around the same time, three Swedes were found guilty of piracy — as in facilitating the sharing of copyrighted material on the Internet. In the widely publicized case of The Pirate Bay, a Bittorrent index service, three techies with the digital world at their fingertips, thumbed their noses at the law and faced, at worst, some time in the notoriously comfortable jails of Sweden.

The obvious analogy and contrast between these two stories is of course an easy target of ironic comment: piracy, old/new, physical/digital, poor/rich. But it also got me thinking about longer term connections. Indeed, which of those two events is more important symbolically for the future political economy of Africa? Which has more to do with the price of injera or ugali?

Armed men attacking ships at sea was a curious manifestation of the 18th century popping up in the 21st century. Western media and comedians in particular reacted to it as they would to a woolly mammoth buried in the permafrost of Siberia for 10,000 years suddenly thawing and starting to ramble around, Jurrassic Park-style. A pirate story is hard to resist, pirates captivate the imagination of kids, they make western adults feel smug about their own “more civilized” society where such things disappeared 200 years ago, but they also have a kind of radical chic, there’s a certain coolness to their image as rebels standing up to “the man”. They are many interesting things, but there’s also a less exotic reality: those pirates are increasing the cost of shipping anything through that part of the Indian Ocean, which in turn affects the cost of everything from food to energy in Somalia, Djibouti, Ethiopia, Kenya, Tanzania and even further inland, endangering the livelihood of millions of people in the region. Like drug traffickers, in reality they harm not only the world at large but mostly their own people. Unfortunately there’s nothing new about that. In fact, the story of Somali pirates over the last few years fits with the well-worn gloom and doom scenarios of Africa in the 21st century: failed states, increased marginalization, the danger of slipping into a modern dark ages, etc. you know the story.

But how about those Swedish Internet pirates? What do they have to do with Africa, where copyrights and patents have never been respected, and where there isn’t enough bandwidth for it to matter on the global scale anyway? A lot actually. It has got to do with something huge that is quietly reshaping the world: the ever expanding scope of intellectual property. Ok, just in case that was not emphasized enough, this is the thing we’re talking about: the expanding scope of intellectual property. The digitization of entertainment and the difficulties that industry faces from file-sharing are merely the tip of the iceberg. By now it’s old news that, thanks to technology, things that were previously easier to limit and control are now easy to copy and share. But also and more importantly, many things which previously were “free” are now going to get entangled in webs of patents, copyrights, trademarks, and so on. And now we are entering the phase where this will profoundly affect the lives of all of humanity, not just the world of computers and information.

Digital coffee – a trip down memory lane

Years ago (”Digital Coffee”, Nov. 1999), I tried to make the link between coffee and intellectual property, using a comparison of buying $1 of Starbucks stock versus $1 of coffee on the commodity markets. So let’s see where we are today with that hypothetical $1. As illustrated in the chart, invested in SBUX stock in 1993, it grew to $6 by 1999, and would be worth $15 in 2009. While the poor dollar invested in coffee itself, which had reached $1.30 in 1999, would continue to inch up, reaching $1.75 by 2009. The conclusion that, if you consider the chain of value that leads to a cup of coffee, “at the end of the chain it’s $100 a pound, while on the commodity markets it’s $1 a pound, and the grower probably gets $0.10″, has been exacerbated. The coffee farmer, despite doing the most difficult part, gets a shrinking share of the total value. Most of the value in the final product of coffee is really information; it’s in the distribution, and marketing of the coffee experience. That “information goods” part of coffee, which is intellectual property even if it’s not rocket science, is worth more and more while the physical commodity is worth relatively less and less. (That doesn’t happen with oil because there’s a finite supply). And it’s a huge market as I pointed out then, coffee is second only to oil among the world’s commodities in total value. Therefore the producers needed to figure out ways of get in on the information goods game.

Fortunately, awareness of this reality has increased dramatically in recent years. For example, a movie called “Black Gold ” brought some attention to the plight of coffee farmers in the global economy. The Ethiopian Intellectual Property Office engaged it in earnest, staked a claim in the digital coffee realm by trademarking some of the Ethiopian coffee names. Starbucks correctly identified this move as encroaching on their territory (the “information goods” side of coffee) and this caused a huge battle which was widely covered. With the help of organizations like Oxfam, the EIPO managed to move the battle to the court of public opinion. Thus Starbucks an extremely successful western corporation of whose brand “social responsibility” is a core part, whose customers are the very stereotype of the bleeding heart liberal, found itself in the position of the big bad exploiter of poor third world farmers. It was a strategy worthy of Sun Tzu’s Art of War: if you are a smaller, move the battle to a territory where your enemy’s superior firepower is worthless. Game over. Starbucks capitulated, and EIPO got not only the trademarks, but a promise from Starbucks to help the country in more ways than before. My hat goes off to EIPO and Oxfam for this.

Would you rather collect rent or charity?

But coffee is only one example. A dutch company called “Soil & Crop Improvement BV” is patenting a method of processing of teff flour. The invention results in a gluten-free flour, which helps people with Celiac disease. Celiac is a common genetic disorder, affecting people all over the world. For example in the United States, more than 2 million people have the disease. The disease makes the victim unable to eat gluten, a protein that is found in wheat, rye, and barley, which covers a pretty large fraction of the typical western diet. Thus gluten-free food has a huge market. Sounds like there might be a lot of money to be made from Teff!

So let’s see what this patented invention consists of. As far as I can tell, it has two main ideas. First, you wait a few weeks after harvest before grinding the teff, so that the “the amount of undigested sugars in the starch” is lower than it would if the grain was ground immediately. Second, you pass it through a sieve, so only the small grains go through. Pretty simple stuff. Which of course is good! Saving lives is great, and simple solutions that save lives are the best. Except the whole patenting thing… You see, there’s this thing called “prior art”. In the many centuries since Teff has been the staple in Ethiopia, surely someone had the idea of waiting a few weeks before grinding it and taking the finer grain! But those ideas now belong to a dutch company, because the Netherlands has the intellectual property infrastructure that Ethiopia doesn’t. The winner is determined not necessarily by an actual innovation but by things like having patent offices, and membership in the World Traded Organization. So if this works out and it turns out that 100 million Celiac disease sufferers will switch to a Teff-based diet, the bulk of the profits will flow to the dutch company, not the Ethiopian teff farmer. Sound familiar? SBUX redux. Except in this case it might even go further. It’s not “just” a marketing and distribution advantage which gives a larger slice of the total value, the patent owner can actually bloc the farmer entirely out of that market!

Now there’s nothing particularly evil about Soil & Crop nor is there about Starbucks. In fact, for what it’s worth, they both seem to try to be “socially responsible” corporations. But there’s a big difference between charity and obligation. Suppose you own a house and a tenant came to you and said: “let me take your house and in exchange, each month that I earn more than I spend, I promise to share some the excess to help your kids go to school, and buy you some gifts” You’d say: “Wow, thanks you are very generous Mr. Potential Tenant. But no thanks, here’s a lease, just sign here and pay me the rent.” Right? In other words, you would prefer to have a profitable business relationship with them, rather than accept their charity. So why, when it comes to multi-billion dollar markets for living products that are indigenous, why should it be considered OK that companies can own the brand, the patents, and all the associated information goods value, thus controlling 90% of the final value, while tossing the original owners a few crumbs of charity? Why is enough for them to make the profits and “give back” on a discretionary basis? Shouldn’t they pay rent instead of give charity? So perhaps the “digital coffee” conclusion didn’t go far enough. Now commodities are not just becoming information i.e. controlled by branding and marketing, they are becoming intellectual property, through copyrights and patents too. But who owns this property and who should own it?

Even the birds and the bees

This question affects more than just the potential export markets. The owners of the intellectual property can actually come and extract money even from people who were doing the same thing they’ve been doing before the patent ever existed! For example, in a famous case, some farmers in Canada are forbidden from growing crops that they use to grow — rapeseed (canola) — because they might accidentally mix patented seeds into their crops. Even if they don’t want to use the new seeds and try to avoid it, because birds and bees (and wind among other things) will accidentally mix seeds over large distances, the farmers will infringe on these patents that belong to Monsanto and have to stop…. even though they are only doing the same thing they did before the patent. They have effectively been check-mated out of their own traditional business.

You might think that could never happen in Africa right? The very idea of enforcing a patent against a farmer in rural Africa seems laughable. But think ahead. Intellectual property is a key condition to participating in World Trade Organization and the international community in general. Even China is being forced to do something about copyrights to please the WTO. Not being part of WTO is a huge handicap, and Ethiopia is trying hard to get in, like any country that wants to be part of the world economy. So at some point, it’s quite possible that Ethiopians could find themselves in the position of having to choose between accepting the established intellectual property system under which they are screwed, or rejecting the system at enormous costs i.e. going the pirate route.

Which brings us back to our Swedish pirates. Putting aside their guilt or innocence, they exist because a huge number of people feel locked out of the “information goods” and these people create an enormous black market for copyrighted movies, music, and software. And bittorrent, the protocol their service facilitates, just happens to be the most efficient current form of file sharing, so they are current poster children, the latest incarnation of Napster, in the on-going saga of intellectual property on the Internet. But it’s not just pirates. The world of property in information is a dangerously unstable one even among the big players. A long time ago, a researcher from IBM explained the world of corporate patents to me as follows. Patents are like nuclear weapons, they don’t want to use them but they have to have them because their opponents have them. They hold them as deterrents, they sign patent “treaties” where they agree not to sue each other and cross-license patents to each other. But sometimes they actually use these “nuclear weapons” i.e. they sue: vast sums of money are extorted, untold hours of effort are expended in futile wars, and companies are driven out of business, etc.

So if things like coffee and teff are going to become information goods, then what kind of world are we heading into? If you extrapolate from other areas where intellectual property dominates, namely software, digital entertainment, and pharmaceuticals, the current trends do not bode well for the vast majority of humanity. It’s a world where the rich get richer and the poor get poorer, much faster than what has occurred with physical commodities over the last couple of centuries. Those who are locked out of the web of intellectual property ownership will be like non-nuclear powers in a nuclear world, except the super-powers won’t be a stable pair, it will be a multi-polar unstable world, with constant threats and actual disastrous fallouts… and of course pirates! Imagine a world of patented food, and the inevitable black market like narcotics today but much much bigger.

But are we really heading toward this dystopian future of bio-patent wielding powerhouses dominating the world, alternately fighting each other and enslaving the rest? Well of course not necessarily. Fortunately, some farsighted people are already on the case some scientists are calling for a bio-patent ban for example. One of them in fact is an Ethiopian. These are scientists, so of course they are not against scientific advancements and their practical use; they are protesting some forms of ownership. Maybe there will be open-source bio-technology and pharmaceuticals, that are as successful and significant as open source software, and all the key processes and ideas of future life will be freely or fairly available to the whole world. But maybe not. What if that open-source nirvana fails to occur? Banning bio-patents may not be the right answer anyway. Until the right balance emerges in this “informationalization” of everything, all sides have to arm themselves to the teeth for intellectual property warfare lest they be marginalized and reduced to piracy. We are probably already in the early stages of a mad scramble, just like the scramble for African raw materials during the industrial revolution/colonial era. Now it’s not grabbing land with timber and gold but about claiming as much as possible of the DNA of plants and animals, patenting potentially lucrative variations of traditional processes… In the case of Ethiopia for example, it’s not just coffee and teff, it’s also (to take random example, I’m sure there are many more) flaxseed, an important source of Omega-3 acids. Hey has anyone filed a patent for a process to create a convenient form of Telba?

US Food Aid Contributing to Africa’s Hunger?

Above: A quarter century after the 1984 famine, which left
millions of Ethiopians destitute, familiar faces still linger as
the country remains dependent on food aid. (Sven Torfinn )

ABC News
By DANA HUGHES
NAIROBI, Kenya, Oct. 29, 2009
Drought-stricken Ethiopia is pleading for food aid again to stave off starvation, but some critics are complaining that the policies of the country’s most generous donor, the United States, is exacerbating the cycle of starvation. A hungry Ethiopia gets 70 percent of its aid from the U.S., but according to a new report by the aid organization Oxfam International, that help comes at a cost. U.S. law requires that food aid money be spent on food grown in the U.S., at least half of it must be packed in the U.S. and most of it must be transported in U.S. ships. The Oxfam report, “Band Aids and Beyond,” claims that is far more expensive and time consuming than buying food in the region. Read More.

Video: Famine eclipses Ethiopia’s beauty and rich history (Worldfocus)

The Huffington Post:
25th anniversary of Ethiopia famine – Has anything changed since?
My colleague Marc Cohen, a senior researcher at Oxfam America, reflects on the 25th anniversary since the devastating famine of 1984 in Ethiopia. He was in the country a few months ago: Twenty-five years ago, Michael Buerk’s dramatic BBC footage from Korem, in northern Ethiopia, brought a devastating famine to the world’s attention. Tens of thousands of people had sought refuge from war and drought in the town. Every 20 minutes, a camp resident died from hunger and related diseases. Buerk called Korem “the closest thing to hell on earth.” Read the whole story: The Huffington Post.

Video: The 1984 Ethiopian famine (BBC)

Related from Tadias archives: We are the World

Above: To raise money for the 1984-1985 famine in Ethiopia,
45 popular singers collaborated to record the charity single
“We Are the World”, co-written by Michael Jackson and
Lionel Richie. They included Harry Belafonte, Stevie Wonder,
Ray Charles, Bob Dylan, The Pointer Sisters, Kenny Rogers,
Diana Ross, Smokey Robinson, Paul Simon, Tina Turner and
many more. (Photo: United Support of Artists for Africa)

The Song Michael Jackson Co-wrote to Benefit Ethiopia
Tadias Magazine
By Tadias Staff
Published: Monday, June 28, 2009
New York (Tadias) – The painfully wrenching images of hungry children, which invaded living rooms around the world in the mid 80′s, prompted Bob Geldof and Midge Ure to organize the 1985 Live Aid concert and ‘raise funds for famine relief in Ethiopia’. The multi-nation event, which showcased some of the biggest names in the music industry, included Michael Jackson, who co-wrote the project’s signature song “We Are the World” along with Lionel Richie. The song was recorded on the night of January 28, 1985, following the American Music Awards. Read more.

Video: We Are The World

25th anniversary of Ethiopia famine – Has anything changed since?

Above: A quarter century after the painfully wrenching images of hungry children invaded living rooms around the world, familiar faces still linger as millions of Ethiopians remain dependent on food aid. (Sven Torfinn Photography)

The Huffington Post:

My colleague Marc Cohen, a senior researcher at Oxfam America, reflects on the 25th anniversary since the devastating famine of 1984 in Ethiopia. He was in the country a few months ago: Twenty-five years ago, Michael Buerk’s dramatic BBC footage from Korem, in northern Ethiopia, brought a devastating famine to the world’s attention. Tens of thousands of people had sought refuge from war and drought in the town. Every 20 minutes, a camp resident died from hunger and related diseases. Buerk called Korem “the closest thing to hell on earth.”

Read the story at The Huffington Post.

Video: The 1984 Ethiopian famine (BBC)


Related:
The Song Michael Jackson Co-wrote to Benefit Ethiopia.

Watch:

Yared Tekabe’s Groundbreaking Research in Heart Disease

Dr. Yared Tekabe runs studies in cardiovascular disease detection and prevention at Columbia University. (Photo by Kidane Mariam for Tadias Magazine)

Tadias Magazine
By Tseday Alehegn

Published: Tuesday, March 17, 2009.

New York (TADIAS) – Dr. Yared Tekabe enjoys doing most of his reflections while sitting anonymously with his laptop at cafés in Harlem. When he’s not there, Tekabe is busy running studies in cardiovascular disease detection and prevention at his lab in Columbia University’s William Black building in upper Manhattan. Last November, Tekabe’s groundbreaking work on non-invasive atherosclerosis detection and molecular imaging was published in the American Heart Association’s journal, Circulation, along with an editorial citing its clinical implications.

Dr Tekabe’s success has helped his laboratory, headed by Dr Lynne Johnson, to receive another $1.6 million four-year grant from the National Institute of Health to continue his research, and Tekabe hopes that in a few years time his work can help heart disease prevention efforts and early detection of atherosclerosis in humans.

“What is atherosclerosis in layman terms?” I ask him, trying hard to correctly pronounce this tongue twister. He breaks it down to its linguistic roots. “Atherosclerosis comes from the Greek roots athere which means gruel, and skleros which means hardness or hardening,” he explains. Further research in Wiki reveals that atherosclerosis is a condition affecting our arterial blood vessels, which transport blood from the heart to the rest of the body. Atherosclerosis is the chronic condition in which inflammation of the walls of our blood vessels lead to hardening of the arteries.

“Atherosclerosis is the underlying cause of cardiovascular disease (CVD),” Tekabe says. “The result is progressive closing of the blood vessels by fat and plaque deposits, which block and further restrict blood flow. In more serious cases it may also lead to clots in the aorta (main artery coming out of the heart) or carotids (arteries supplying blood to the brain) that may dislodge and travel to other parts of the body such as the brain, causing stroke. If the clot is in the leg, for example, it can lead to gangrene. Deposits of fat and inflammatory cells that build up in the walls of the coronary arteries (supplying blood to the heart muscle) can rupture leading to blood clots. Such clots in an artery that supplies blood to the heart muscle will suddenly close the artery and deprive the heart muscle of oxygen causing a heart attack. In the case of very sudden closure of an artery a clot can cause sudden cardiac death.”

“It’s the Tim Russert story,” Tekabe says, providing a recent example of what undetected levels of plaque formation in our bodies can lead to. EverydayHealth.com, an online consumer health portal, had described the famed former MSNBC ‘Meet the Press’ host’s sudden heart attack as being caused by a plaque rupture in a coronary artery. Russert had previously been diagnosed with heart disease, but his atherosclerosis was asymptomatic. He had not experienced the common signs of chest pain and other heart attack symptoms to warn him or his doctors of his true condition. The undetected inflammation in his vessels and the subsequent rupture of plaque led to his sudden heart attack and untimely death. This is not uncommon, however. According to the Centers for Disease Control and Prevention (CDC), heart disease “is the leading cause of death for both women and men in the United States, and women account for 51% of the total heart disease deaths.” There is even more grim news: United States data for 2004 has revealed that the first physical symptom of heart disease was heart attack and sudden death for about 65% of men and 47% of women with CVD.

The risk factors for atherosclerosis are well known and Tekabe runs through the list with me: “diabetes, obesity, stress, smoking, high blood pressure, family history of CVD, and diet” he says. “But of all the factors that I have mentioned, I would say diet is the most important one to change,” he adds. Food items such as red meat, butter, whole milk, cheese, ice cream, egg yolk, and those containing trans fat all put us at higher risk for plaque formation. The American Heart Association recommends eating fish such as salmon, herring and trout instead of red meat, as well as eating food that is steamed, boiled or baked instead of fried. It is better to use corn, canola, or olive oil instead of butter, and to eat more fiber (fruit, vegetables, and whole grain). Notwithstanding that March is deemed National Nutrition Month by the American Heart Association, changing our diet is largely emphasized in CVD prevention. We should also be exercising at least 30 minutes each day.

“Early non-invasive detection of the presence of inflammation and plaque could save lives,” Tekabe points out. “But the problem is two-fold: those who suffer from atherosclerosis do not display warning signs until it’s too late, and for doctors, a non-invasive method of detecting atherosclerosis is by and large not a possibility.” Research by Tekabe and others may soon change the way doctors can detect atherosclerosis.

Using molecular imaging techniques that were previously popular in cancer biology research, Tekabe and his colleagues have discovered non-invasive methods of detecting RAGE, a receptor first discovered in 1992 and thought to have causative implications in a host of chronic diseases ranging from diabetes to arthritis. Tekabe, collaborating with Dr Ann Marie Schmidt who has shown that RAGE receptors play a key role in atherosclerotic inflammatory response, notes that these receptors can be detected non-invasively in mice that have been fed a high-fat, high cholesterol diet.

“In the past, although we knew about the RAGE receptor, especially in the study of diabetes, we were not able to detect it without performing an autopsy of the lab mice. Clearly, in the case of humans it would be pointless if we said that we detected atherosclerosis in the patient after the patient had died,” Tekabe explains. “Therefore, it was imperative that our research showed a more non-invasive method, detecting RAGE receptors and locations of inflammation while the subject was still alive. The first step would be to test it on mice, which we have, and then perhaps on larger animals such as pigs, so that this research could be successfully translated to help non-invasively detect atherosclerosis in its early stages in human beings.”

Left Image: Atherosclerotic aorta: The image is from a mouse fed a Western type of fat diet (high-fat, high cholesterol diet) for 34 weeks. It shows complete blockage of the aorta and the branches that supply the brain. The plaque is made up of fat and inflammatory cells.
Right Image: Relatively normal aorta: This is from 6 weeks old mouse fed a normal diet.

Tekabe’s recently published research showing detection of RAGE receptors responsible for arterial inflammation was funded by a grant from the American Society of Nuclear Cardiology as well as from an American Heart Association Heritage Foundation award.

The November Circulation editorial entitled “Feeling the RAGE in the Atherosclerotic Vessel Wall” highlights the significance of Tekabe et al’s findings and the necessity for early detection of atherosclerosis. “This is an exciting development that adds an important marker of atherosclerotic disease that can now be assessed non-invasively,” write Drs. Zahi Fayad and Esad Vucic. “Tekabe et al demonstrate, for the first time, the noninvasive specific detection of RAGE in the vessel wall.” They concur with Tekabe that “noninvasive detection of RAGE in the vessel wall could help define its role in plaque rupture, which has potentially important clinical implications.”

Tekabe came to Boston in 1990 and subsequently completed his Bachelor’s degree in Biotechnology and his Masters and PhD in Biomedical Sciences with a focus on CVD and drug development. His academic choices have inevitably led him to his career as a scientist, but he has personal reasons for choosing this path as well.

“I was born in Dire Dawa, Ethiopia. I have 1 brother and 8 sisters, and my parents had no formal education. But my father always encouraged me to seek higher education. While I was completing my studies I witnessed my beloved father suffer from Coronary Artery Disease (CAD) and he underwent triple bypass surgery. He passed away in 2004, and I promised myself that I would step up to the challenge of finding a way to prevent heart disease” Tekabe says in a somber and determined tone. “Heart disease is the leading cause of death in the developed world, and I am motivated by that challenge, but this research is also deeply personal.”

Tekabe hopes that his research will be applicable to other areas where RAGE receptors have been hypothesized to play a central role. Circulation editors who follow Tekabe’s work have noted that “in addition to its role in atherosclerosis and the development of vascular complications in diabetes, RAGE possesses wider implications in a variety of diseases, such as arthritis, cancer, liver disease, neurodegenerative disease, and sepsis, which underscores the importance of the ability of its noninvasive detection.” Tekabe, as part of Dr Ann Marie Schmidt’s team, has already filed U.S. and international patents and has plans to jump-start a drug development arm of the pharmaceutical industry in Ethiopia. “I’m looking for interested sponsors in Ethiopia who can see the potential of this research and its global implications,” he states.

Now that Forbes has apprised us of the billionaire status of an Ethiopian-born businessman, we hope this news may peak his interest in helping to start scientific research initiatives in Ethiopia.
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Tseday Alehegn is Co-Founder & Editor-in-Chief of Tadias Magazine.

Our Beef with Kitfo: Are Ethiopians in America Subscribing to the Super Sizing of Food?

Photo by Ayda Girma for Tadias

Tadias Magazine
By Dr. Asqual Getaneh & Dr. Adam Waksor

Updated: Saturday, August 23, 2008

New York (TADIAS) – Every few years a new fad diet, which promises to slim, beautify, energize and prolong life hits the media and ends up on the shelves and kitchen tables of America. It is a staggering 30 billion dollar market. Paradoxically, Americans continue to expand and suffer significant obesity related morbidities. Ethiopians in the U.S. usually ridicule the folly of these diets. We also do not heed the numerous sound directives from the U.S. Surgeon General on healthy diet, tobacco cessation and exercise. Celebrating one of the most complex cuisines in the world, most of us continue to indulge in the sinfully rich kitfo, downing it with a stiff Black Label as often and as much as possible and with humor. Some of us finish off with a well-branded cigarette.

True, a few of us might choose the heart friendly red wines; and humor does contribute to healthy arteries. The effect, even so, is an ever growing mid-riff, inflamed and clogged arteries and the associated health problems. Anecdotal information shows that the prevalence of diabetes, high blood pressure and high cholesterol are on the rise both among Ethiopians living in the West and the affluent urbanized population in Ethiopia. These conditions, individually and together with tobacco, are the leading causes of heart attacks and strokes. Among Ethiopians in the U.S., a coronary artery bypass surgery after an unexpected heart attack in a man in his 40’s is no longer a rare occurrence. In fact he is considered lucky to have survived.

Ethiopians living in the West (or the urbanized in Ethiopia), in general, have undergone a nutrition transition. In content, our diet has changed from a relatively diversified menu, which included legumes (shiro), vegetables (like gomen) and high fiber grains (teff) to an almost exclusively meat-centered (kitfo/tibs), refined carbohydrates (rice/wheat based injera) and animal fat diet (kibae). In quantity, we have subscribed to the American super sizing of food, or in Ethiopian restaurant parlance – a “combination plate”. Large quantities of rich food, which would have been eaten over several days in Ethiopia are consumed as a meal. Thanks to the many Ethiopian eateries and tireless family members who pack luggages full of food, there is easy access to a cheap, familiar and delectable meal every day. In addition, we have an appetite for fatty and spicy cooking. The preference for fat might be biological and not unique to Ethiopians. The key however is our conscious contribution to a sustained fat consumption, which in itself leads to changes in our brain. As a result, our appetite cues and energy expenditure are negatively influenced. In a nutshell fat begets fat through a complex neurological and chemical regulation.

Not only are we consuming high fat and large portions of food, but also our lifestyle has not kept up with our energy consumption. Unless expended, the body stores all excess energy from dietary fat, alcohol or vegetables as body fat for use in time of caloric need. In affluent societies there is no time of need if it is not artificially introduced, for example as aerobic exercises. A high-energy diet requires a consciously planned parallel program of energy expenditure. Admittedly, having an exercise plan and adhering to it is difficult in the era of long-commutes, parking garages, office jobs and the rush to attain the trappings of life in the West. Our relaxation and socialization also revolves around elaborate meat-centered feasts and alcohol and not enough around physical activity.

Besides its many direct toxic effects on brain, blood and liver cells, drinking moderate to heavy alcohol limits one’s exercise capacity. It increases the risk of dehydration through its diuretic effect and reduces endurance and blood sugar levels limiting the duration of physical activity. Heavy alcohol use also contributes to weight gain, which in turn limits exercise capacity. However, it has been shown that low to moderate consumption of alcohol has beneficial effects on energy intake and on lipid (cholesterol) profile.

We admit that Kitfo and alcohol together do not have as much devastating effect as cigarette smoking on health. Sporting Marlboro Light, Camel or Winston reeks havoc on the human body from skin changes, to cancers to heart attacks and strokes. If one were to do only one thing today to benefit his health, smoking cessation will be the most important step towards better health. However, we will leave this main health hazard for a later issue.

So, our beef with kitfo is its frequent and excessive use, its high content of butter, its frequent coupling with heavy alcohol and smoking in many cases, and the lack of any mitigating lifestyle habits such as exercising, a balanced diversified diet and normal weight.

A few tips…

*Keep kitfo and other heavy fat meals as delicacies, for special occasions.

*Keep your midriff slim without plastic surgery. Plastic surgery does not have beneficial effect on health as loss of abdominal fat. Know your waist to hip circumference ratio and keep at goal. This ratio should be less than 0.8 for women and less than one for men.

*Know your body mass index (BMI) and keep at goal: BMI is calculated as follows. Weight in kilogram divided by height in meters squared. A BMI between 18.5 and 24.9 refl ects normal weight. Between 25 and 29.9 is considered overweight. Over 30 is in the obese range, which is associated with a significant risk for developing diabetes, high blood pressure and their complications, arthritis, liver and gall bladder diseases.

*If the portion of meat is more than the size of your palm (3 ounces or 85 grams), it is too much. And, in general you should not have more than two of these a day.

*A gram of fat has 8 calories, a gram of protein and carbohydrates have 4 calories and a gram of alcohol has 7 calories (one teaspoon of butter has 5 grams of fat).

*If your plate does not contain more than one color, you are not getting adequate nutrition and are most likely consuming more calories than you need. Different colors in fruits and vegetables are a low caloric source of various vitamins and minerals.

*If you are having more than 5 drinks a week, your body is taking too much. More than two units for women and three units of alcohol a day for men are excessive.

*Cigarettes are passé and no longer chic or cool.

“The Wogesha Will See You” Traditional Ethiopian Medicine, Then and Now

Traditional medicine has been defined by the World Health Organization (WHO) as “the sum total of all knowledge and practices, whether explicable or not, used in the diagnosis, prevention and elimination of physical, mental or social imbalances and relying exclusively on practical experience and observation handed down from generation to generation, whether verbally or in writing.” This system of health care is also known as folk medicine, ethnomedicine, or indigenous medicine. In some countries, including the US, the terms complementary or alternative medicine are used interchangeably for traditional medicine.

It is generally accepted that traditional Ethiopian medicine is the outcome of long and dynamic interactions among African, Greek, Arabic, and Hebrew traditions. These interactions, combined with the variations in the country’s unique ecology and diverse ethnic groups, make the traditional medical system in Ethiopia very rich and complex. Records show that the existence of such a health care system can be traced back to the period prior to the 16th century. Although the expansion of modern medicine appears to influence some aspects of the traditional system, traditional Ethiopian medicine remains rooted in magico-religious beliefs and empirical knowledge from the natural environment.

An estimated 80% of the Ethiopian population relies on traditional medicine. Socio-cultural appeal, accessibility, affordability, and effectiveness against a number of health problems seem to foster its widespread use. Consistent with the increasing global interest in alternative medicine, the demand for traditional medical therapies in Ethiopia is on the rise. In 1986 over 6,000 practitioners were registered with the Ministry of Health. More recently, the Ethiopian Traditional Healers’ Association, which was established in 1987, reported a membership of 9,000 healers. A few experts estimate the number of traditional medicine practitioners, vendors, and collectors in the country at more than 80,000.